What Are The Side Effects Of Metandienone?

Side effects of Metandienone

Metandienone is a potent anabolic‑steroid that can lead to several adverse effects, especially when used in excess or for prolonged periods:

Hormonal imbalance: Suppression of natural testosterone production, leading to decreased libido, erectile dysfunction, and infertility.

Cardiovascular strain: Elevated blood pressure, altered lipid profiles (increased LDL, decreased HDL), and potential increases in the risk of myocardial infarction or stroke.

Hepatic stress: In high doses, especially oral preparations, can cause liver enzyme elevations, jaundice, or hepatotoxicity.

Dermatological reactions: Acne, oily skin, hair loss (male‑pattern baldness), and seborrheic dermatitis.

Psychological effects: Mood swings, irritability, aggression ("roid rage"), anxiety, and in some cases depression or psychosis.

Gynecomastia due to peripheral aromatisation of testosterone into estrogen.

3. Summary

Twelve‑week protocol: 50 mg/week for the first 8 weeks (total 400 mg), then 25 mg/week for weeks 9‑12 (total 100 mg).

Rationale: This dosage keeps blood levels within the therapeutic window, minimises side‑effects, and avoids the risk of "burnout" or acute toxicity that can arise from a single high dose.